Studies on curative efficacy of monoterpene eugenol on anti- leukemic drug arsenic trioxide induced cardiotoxicity.

@article{Binu2017StudiesOC,
  title={Studies on curative efficacy of monoterpene eugenol on anti- leukemic drug arsenic trioxide induced cardiotoxicity.},
  author={P. J. Binu and N. Anupama Sai Priya and Surendran Abhilash and Radhakrishnan Chandraprabha Vineetha and Raveendran Harikumaran Nair},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2017},
  volume={91},
  pages={559-566}
}
BACKGROUND Arsenic trioxide (As2O3) is emerging as a frontline agent for the treatment of acute promyelocytic leukemia (APL) but the therapeutic application is limited by its toxicity. QT prolongation, torsades de pointes and sudden cardiac death have been implicated in the As2O3 therapy. So eugenol is a monoterpene compound is well known for its… CONTINUE READING