Studies on cardioactive steroids. V. Structure-activity relationships of derivatives of 16 alpha-gitoxin.

Abstract

The potency of 17 derivatives of 16 alpha-gitoxin was tested in the isolated atrium and heart of the guinea pig and the contractility-increasing activity of the 16 alpha-gitoxin 16 alpha-acetate was compared with that of 16 alpha-gitoxin in the anesthetized dog. The potency of 16 alpha-gitoxin was increased by the substitution of 16 alpha-OH for 16 alpha… (More)

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Cite this paper

@article{Haustein1980StudiesOC, title={Studies on cardioactive steroids. V. Structure-activity relationships of derivatives of 16 alpha-gitoxin.}, author={K. O. Haustein and Erika Glusa}, journal={Pharmacology}, year={1980}, volume={21 6}, pages={375-82} }