Studies on calcium transport system in cardiac sarcoplasmic vesicles and its inhibition by dl-propranolol.

  • Saori Fujita
  • Published 1976 in
    Archives internationales de pharmacodynamie et de…


Fragmented sarcoplasmic reticulum was prepared from the rabbit heart. The function of vesicles was characterized by the activities of Mg++ and ATP-dependent 'Calcium-Binding' and Ca-ATPase. A fluorescence probe, 1-anilino-8-naphthalene sulfonate (ANS) was employed to examine the physicochemical changes in vesicular membranes. Chlorpromazine, dl-propranolol… (More)


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