Studies on antibiotic 230 as a molluscicide.


In the course of studying molluscicidal effects of microorganisms, a microorganism belonging to Streptomycetaceae, Streptomyces griseolus (Strain 230) was isolated from soil and a certain microbial ingredient proved to have a molluscicidal activity. The effective substance was named antibiotic 230. As a result of several investigations on the antibiotic, the following chemical features were made clear. The chemical substance was an indol-carbazole-heterocyclic compound, the molecular weight 446 and the molecular formula C28H26N4O3. The antibiotic demonstrated a molluscicidal effect against Oncomelania snails and their eggs both in the laboratory and in the field. The compound had a wide bacteriostasis spectrum and a slight toxicity to fish in addition to the above, but it was non-toxic to plants.

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@article{Chaosu1993StudiesOA, title={Studies on antibiotic 230 as a molluscicide.}, author={Y Chaosu and D-E. Hu and Mingxin Shi and Guangchun Hu}, journal={Japanese journal of medical science & biology}, year={1993}, volume={46 3}, pages={103-19} }