Studies on an abnormally sharpened elution peak observed in counter-current chromatography.

@article{Ito1992StudiesOA,
  title={Studies on an abnormally sharpened elution peak observed in counter-current chromatography.},
  author={Yoichiro Ito and Yoichi Shibusawa and Henry M. Fales and H J Cahnmann},
  journal={Journal of chromatography},
  year={1992},
  volume={625 2},
  pages={177-81}
}
Counter-current chromatography (CCC) of the bromoacetylation product of 3,3',5-triiodo-L-thyronine (T3) produced an unusually sharp peak for the desired product, N-bromoacetyl T3 (BrAcT3). A series of experiments revealed that bromoacetic acid, probably present as a side reaction product in the sample solution, was responsible. This compound repressed the… CONTINUE READING