Studies on aculeacin. I. Isolation and characterization of aculeacin A.

Abstract

Aculeacin A, a new antifungal antibiotic was isolated from the mycelial cake of Aspergillus aculeatus M-4214. The antibiotic is a white amorphous powder soluble in lower alcohols and hardly soluble in other organic solvents or water. Aculeacin A gave palmitic acid and five ninhydrin-positive products including theonine, hydroxyproline upon acid hydrolysis. The antibiotic showed a potent activity against molds and yeasts, but exhibited no antibacterial activity. Aculeacin A has relatively low toxicity in mice.

Cite this paper

@article{Mizuno1977StudiesOA, title={Studies on aculeacin. I. Isolation and characterization of aculeacin A.}, author={Kyosuke Mizuno and Akemi Yagi and Sohei Satoi and Masahiko Takada and M Hayashi}, journal={The Journal of antibiotics}, year={1977}, volume={30 4}, pages={297-302} }