Studies on Rabbit Lymphocytes in Vitro

  title={Studies on Rabbit Lymphocytes in Vitro},
  author={Philip G. H. Gell and Stewart Sell},
  journal={The Journal of Experimental Medicine},
  pages={813 - 821}
Specific antisera directed against all six of the well characterised allotypic determinants of rabbit IgG (As1, 2, 3, 4, 5, and 6) are capable of inducing blast transformation and DNA synthesis when added to lymphocyte cultures obtained from donor rabbits having the appropriate IgG allotype. Mixtures of antisera directed against two different allotypic determinants induce a "summation" of transformation and DNA synthesis over and above the effect of mixtures of two antisera directed against the… CONTINUE READING

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