Studies on Progressive Metabolic Alterations in Thioacetamide Induced Hepatocarcinogenesis

@article{Bhide1970StudiesOP,
  title={Studies on Progressive Metabolic Alterations in Thioacetamide Induced Hepatocarcinogenesis},
  author={Sumati V. Bhide},
  journal={British Journal of Cancer},
  year={1970},
  volume={24},
  pages={504 - 509}
}
Gene-targeted iMycEμ mice that carry a His6-tagged mouse Myc(c-myc)cDNA, MycHis, just 5' of the immunoglobulin heavy-chain enhancer, Eμ, are prone to B cell and plasma cell neoplasms, such as lymphoblastic B-cell lymphoma (LBL) and plasmacytoma (PCT). Cell lines derived from Myc-induced neoplasms of this sort may provide a good model system for the design and testing of new approaches to prevent and treat MYC-driven B cell and plasma cell neoplasms in human beings. To test this hypothesis, we… CONTINUE READING
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