Studies on Local Irritation of DA-3585, A Recombinant Human Erythropoietin, in Rabbits

@inproceedings{Cho1998StudiesOL,
  title={Studies on Local Irritation of DA-3585, A Recombinant Human Erythropoietin, in Rabbits},
  author={Hyeon Min Cho and Dong-Hwan Kim and Kyung-Koo Kang and Jang-Hyeon Park and Sung-Hee Lee and Won Bae Kim},
  year={1998}
}
As a series of safety studies on DA-3585, a recombinant human erythropoietin, its local irritancy was examined in rabbits after the following treatments; application into the conjunctival sac of the eye(single), subcutaneous injection (single and -day repeated)and intravenous injection (7-day repeated.)In addition, perivascular irritation of DA-3585 was investigated in mice. In the result of ocular irritation test, 10,000IU/ml solution of DA-3585 could be considered as a non-irritating material… CONTINUE READING

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