Studies on Experimental and Clinical Hypochloremia in Man.


In a recent study (1), it was demonstrated that severe hypochloremia and alkalosis could be induced gradually in the dog, by means of continued loss of chloride, without the development of a marked azotemia or detectable renal injury. Kerpel-Fronius (2), Kerpel-Fronius and Butler (3), Ambard (4), and Hiatt (5) had previously made similar observations in the dog and rabbit. The purpose of the present investigation was to determine whether or not the same situation could be induced in man.

Cite this paper

@article{Kirsner1943StudiesOE, title={Studies on Experimental and Clinical Hypochloremia in Man.}, author={Joseph B. Kirsner and W L Palmer and K Knowlton}, journal={The Journal of clinical investigation}, year={1943}, volume={22 1}, pages={95-102} }