Nowadays the Compton scattering is widely applied in various fields. In the present paper, we explore the Compton scattering effects on the binary powder mixture scatterers. By using the Compton scattering theory, we obtain an approximate linear relationship between the scattered photon counts and the contents of the binary powder mixture scatterer. This relationship has been confirmed by conducting the Compton scattering experiments of the binary powder mixture series such as the Fe-C, Fe-Cu and Ni-Cu scatterers. Moreover, we make a discussion on the experimental errors. The Compton scattering method is helpful for measuring the contents of the binary powder mixtures.