Studies ofSalvia divinorum (Lamiaceae), an Hallucinogenic mint from the Sierra Mazateca in Oaxaca, Central Mexico

  title={Studies ofSalvia divinorum (Lamiaceae), an Hallucinogenic mint from the Sierra Mazateca in Oaxaca, Central Mexico},
  author={Leander J. Valdes and G. M. Hatheld and Masato Koreeda and Ara G. Paul},
  journal={Economic Botany},
Salvia divinorum Epling & Mtiva-M. is one of the vision-inducing plants used in ritual curing by the Mazatec Indians of central Mexico. The present status of research is summarized. Experiments with material collected at different Oaxacan sites confirmed that the mint has white (rather than blue) flowers with a purple calyx and that flowering is induced by short day length. 
The chemistry of Salvia divinorum
Salvinorin A (1a), a neoclerodane diterpenoid isolated from the plant, is a potent, selective agonist at the κ opioid receptor (KOR), and is the first non-nitrogenous opioid.
The Use of Salvia divinorum from a Mazatec Perspective
This chapter will try to clarify the best ways to use Salvia divinorum for medicinal, psychotherapeutic, and inner exploration purposes.
DNA identification of Salvia divinorum samples.
Evolution and origins of the Mazatec hallucinogenic sage, Salvia divinorum (Lamiaceae): a molecular phylogenetic approach
The molecular phylogenetic results suggest that S. divinorum should not be classified within Dusenostachys and that it is not a hybrid, and it is determined that the closest known relative of this psychoactive Mexican sage is S. venulosa, a rare endemic of Colombia.
Daniel: It might be more fitting to ask, “When did Salvia divinorum first become interested in me?” I first came across a description of Salvia divinorum in 1973 in a little booklet entitled Legal
Salvia divinorum: enigma psicofarmacológico y resquicio mente-cuerpo
SUMMARY In the present paper, the multidisciplinary research on Salvia divinorum and its chemical principles is analyzed regarding whether the ethnobotany, phytochemistry, psychopharmacology, and
The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation‐induced hypermotility in mice
  • R. CapassoF. Borrelli A. Izzo
  • Biology, Medicine
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2008
It is concluded that salvinorin A may reduce motility through activation of different targets, both in physiological states and during croton oil‐induced intestinal inflammation.
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues.
Further modification of salvinorin A (1a), the major active component of Salvia divinorum, has resulted in the synthesis of novel neoclerodane diterpenes with opioid receptor affinity and activity.
Systematics and Ethnobotany of Salvia Subgenus Calosphace and Origins of the Hallucinogenic Sage, Salvia divinorum
Phylogenetic analysis of the combined data set established the monophyly of nine sections and four major lineages within Salvia subgenus Calosphace, the largest of 5 subgenera with some 500 species and strongly supported as monophyletic.


Salvinorin, a new trans-neoclerodane diterpene from Salvia divinorum(Labiatae)
Salvinorin, isolated from Salvia divinorum, has been shown by spectroscopic and X-ray-crystallographic methods to be a trans-neoclerodane diterpene of structure (1). Crystals of compound (1) are
Splendidin, a new trans-clerodane from Salvia splendens
Splendidin, isolated from Salvia splendens(Labiatae) has been shown by 1H and 13C n.m.r. determinations to be 1,11-diacetoxy-15,16-epoxy-trans-cleroda-2,13(16),14-trieno-12,17:19,18-dilactone (2).
Salviarin, a new diterpenoid from Salvia splendens
Salviarin has been shown by a combination of spectroscopic and X-ray methods to be 15,16-epoxy-trans-cleroda-2,13(16), 14-trieno-12,17;19,18-dilactone (1).
Notes on the Present Status of Ololiuhqui and the Other Hallucinogens of Mexico
  • R. Wasson
  • Linguistics
    Botanical Museum leaflets, Harvard University
  • 1963
Picietl, peyotl, teonanacatl, and ololiuhqui these were the four great divinatory plants of Mexico at the time of the Conquest. We give the names in Nahuatl, the lingua franca of that time, spoken as
Morning Glory Tissue Cultures: Growth and Examination for Indole Alkaloids
The seeds and aerial portions of three Ipomoea violacea varieties and the roots, callus tissue, and callus medium of Rivea corymbosa; and the seeds of three Japanese morning glory varieties contained traces of indole alkaloids.
Hydraulic Development and Ethnocide: The Mazatec and Chinantec People of Oaxaca, Mexico
~ government through regional development agencies. It can be shown that ethnocidal policies of these agencies have an intimate relationship with the broad economic and political goals of the federal
Effect of Drugs on Emotional Behaviour in Rats
It is suggested that chlorpromazine reduces fear motivation and that this is independent of its sedative action or of an effect on motor co-ordination.
Effect of Monoamine Oxidase Inhibitors on the Behaviour of Rats in Hall's Open Field
Assessment of the potency of monoamine oxidase inhibitors in vivo based on direct measurement of tissue levels of catecholamine, serotonin or some metabolite thereof and the ability of the inhibitor to potentiate or nullify the effects of some other drug.