Studies of two kinds of virus particles which comprise influenza A2 virus strains. III. Morphological characteristics: independence to morphological and functional traits.

@article{Choppin1960StudiesOT,
  title={Studies of two kinds of virus particles which comprise influenza A2 virus strains. III. Morphological characteristics: independence to morphological and functional traits.},
  author={Purnell W. Choppin and James M Murphy and Igor Tamm},
  journal={The Journal of experimental medicine},
  year={1960},
  volume={112},
  pages={
          945-52
        }
}
Seven strains of influenza A2 virus were serially passed in the chick embryo, and morphological characteristics of the passages were examined in the electron microscope. With serial passage there was a change from a prominently filamentous appearance in early passages to an almost entirely spherical appearance in later passages. The number of passages required for the conversion to spherical morphology varied with different strains. The filament-sphere variation was found to be independent of… CONTINUE READING

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