Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars.

@article{Bock2005StudiesOT,
  title={Studies of transforming growth factors beta 1-3 and their receptors I and II in fibroblast of keloids and hypertrophic scars.},
  author={Oliver Bock and Hai-Yan Yu and Swantje Zitron and Ardeshir Bayat and Mark W. J. Ferguson and Ulrich Mrowietz},
  journal={Acta dermato-venereologica},
  year={2005},
  volume={85 3},
  pages={216-20}
}
Keloids are benign skin tumours occurring during wound healing in genetically predisposed patients. They are characterized by an abnormal deposition of extracellular matrix components, particularly collagen. There is uncertain evidence that transforming growth factor-beta (TGFss) is involved in keloid formation. Therefore we investigated the expression of TGFss1, 2 and 3 and their receptors in keloids, hypertrophic scars and normal skin. Dermal fibroblasts were obtained from punch biopsies of… CONTINUE READING