Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA.

@article{Hays1998StudiesOT,
  title={Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA.},
  author={S L Hays and A. A. Firmenich and P. Massey and Rajat Banerjee and Paul Berg},
  journal={Molecular and cellular biology},
  year={1998},
  volume={18 7},
  pages={4400-6}
}
The RFA1 gene encodes the large subunit of the yeast trimeric single-stranded DNA binding protein replication protein A (RPA), which is known to play a critical role in DNA replication. A Saccharomyces cerevisiae strain carrying the rfa1-44 allele displays a number of impaired recombination and repair phenotypes, all of which are suppressible by overexpression of RAD52. We demonstrate that a rad52 mutation is epistatic to the rfa1-44 mutation, placing RFA1 and RAD52 in the same genetic pathway… CONTINUE READING

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