Studies of the humoral factors produced by layered chondrocyte sheets.

@article{Hamahashi2015StudiesOT,
  title={Studies of the humoral factors produced by layered chondrocyte sheets.},
  author={Kosuke Hamahashi and Masato Sato and Masayuki Yamato and Mami Kokubo and Genya Mitani and Satoshi Ito and Toshihiro Nagai and Goro Ebihara and Toshiharu Kutsuna and T. Okano and Joji Mochida},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2015},
  volume={9 1},
  pages={24-30}
}
The authors aimed to repair and regenerate articular cartilage with layered chondrocyte sheets, produced using temperature-responsive culture dishes. The purpose of this study was to investigate the humoral factors produced by layered chondrocyte sheets. Articular chondrocytes and synovial cells were harvested during total knee arthroplasty. After co-culture, the samples were divided into three groups: a monolayer, 7 day culture sheet group (group M); a triple-layered, 7 day culture sheet group… CONTINUE READING