Studies of the effects of essential fatty acid deficiency in the rat.

@article{Cox1982StudiesOT,
  title={Studies of the effects of essential fatty acid deficiency in the rat.},
  author={Jeffrey W. Cox and Gregory W. Rutecki and L{\'o}pez Francisco and Thomas F. Ferris},
  journal={Circulation research},
  year={1982},
  volume={51 6},
  pages={694-702}
}
We report a model of prostaglandin depletion induced in rats by fasting for 11 days, followed by institution of an essential fatty acid-deficient diet. Urinary prostaglandin E, 2 weeks after this diet had been implemented, was 22 +/- 2 ng/24 hours compared to 113 +/- 8.5 ng/24 hours in controls (P less than 0.01). There was no difference in 24-hour urine… CONTINUE READING