Studies of sodium channels in rabbit urinary bladder by noise analysis

@article{Lewis1984StudiesOS,
  title={Studies of sodium channels in rabbit urinary bladder by noise analysis},
  author={Simon A. Lewis and Mark S. Ifshin and Donald D. F. Loo and Jared M. Diamond},
  journal={The Journal of Membrane Biology},
  year={1984},
  volume={80},
  pages={135-151}
}
Sodium channels in rabbit urinary bladder were studied by noise analysis. There are two components of short-circuit current (I sc) and correspondingly two components of apical Na+ entry, one amiloride-sensitive (termedI A and the A channel, respectively) and one amiloride-insensitive (I L and the leak pathway, respectively). The leak pathway gives rise tol/f noise, while the A channel in the presence of amiloride gives rise to Lorentzian noise. A two-state model of the A channel accounts well… CONTINUE READING
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