Studies of nitric oxide generation from salivary nitrite in human gastric juice.

@article{Iijima2003StudiesON,
  title={Studies of nitric oxide generation from salivary nitrite in human gastric juice.},
  author={Kazuyoshi Iijima and Valerie Fyfe and Kenneth E. L. McColl},
  journal={Scandinavian journal of gastroenterology},
  year={2003},
  volume={38 3},
  pages={
          246-52
        }
}
BACKGROUND Saliva contains substantial concentrations of nitrite derived from the enterosalivary recirculation of dietary nitrate. METHODS We have investigated factors in gastric juice influencing the fate of nitrite in swallowed saliva. When nitrite (100 microM) is added to human gastric juice pH 1.5 or pH 2.5 at 37 degrees C containing physiological concentrations of thiocyanate (1 mM) and ascorbic acid (200 microM), it is converted to nitric oxide within a few seconds. RESULTS The… CONTINUE READING
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