Studies of individuals with schizophrenia never treated with antipsychotic medications: a review.

@article{Torrey2002StudiesOI,
  title={Studies of individuals with schizophrenia never treated with antipsychotic medications: a review.},
  author={E. Fuller Torrey},
  journal={Schizophrenia research},
  year={2002},
  volume={58 2-3},
  pages={101-15}
}
A review of 65 studies of individuals with schizophrenia who had never been treated with antipsychotic medications indicates significant abnormalities in brain structure and function. Neurological and neuropsychological measures show the most consistent and largest group differences between those affected and normal controls. Measures of structural differences and cerebral metabolic function are significant but less impressive. Electrophysiological differences also are found, but most such… CONTINUE READING