Studies of capsule and capsular space of cat muscle spindles.

@article{Fukami1986StudiesOC,
  title={Studies of capsule and capsular space of cat muscle spindles.},
  author={Y. Fukami},
  journal={The Journal of physiology},
  year={1986},
  volume={376},
  pages={281-97}
}
  • Y. Fukami
  • Published 1986 in The Journal of physiology
The presence of hyaluronate in the capsular space of the cat muscle spindle was demonstrated using alcian blue staining at various pHs, the critical electrolyte concentration technique and hyaluronidase treatment. In spindles with intact capsules an extracellular marker, the dye Ruthenium Red, gained access to the capsular space through the gap in the sleeve region, but for a limited distance. In muscle spindles with the capsule nicked, the marker diffused into the capsular space in the… CONTINUE READING

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The limited diffusion is probably due to electrostatic binding of the dye , which is a hexavalent cation , to negatively charged glycosaminoglycan hyaluronate that is present in the space .
The limited diffusion is probably due to electrostatic binding of the dye , which is a hexavalent cation , to negatively charged glycosaminoglycan hyaluronate that is present in the space .
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