Studies of antigen binding on human basophils. II. Continued expression of antigen-specific IgE during antigen-induced desensitization.

Abstract

We previously postulated that desensitization of human basophils was due to endocytosis or shedding of IgE and/or its Fc receptor. We report here, however, that during a 3-hr desensitization of purified basophils, there was no loss of cell surface antigen-specific IgE. The specific desensitization induced by antigen persists for at least 24 hr whereas… (More)

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Cite this paper

@article{Macglashan1983StudiesOA, title={Studies of antigen binding on human basophils. II. Continued expression of antigen-specific IgE during antigen-induced desensitization.}, author={Donald W Macglashan and M Mogowski and L. M. Lichtenstein}, journal={Journal of immunology}, year={1983}, volume={130 5}, pages={2337-42} }