Studies of alteration of hepatic cholesterol metabolism in puromycin-induced nephrotic syndrome in rats.

@article{Thabet1993StudiesOA,
  title={Studies of alteration of hepatic cholesterol metabolism in puromycin-induced nephrotic syndrome in rats.},
  author={Mohamed Alaa Eldin Hassan Thabet and Anna S. Challa and James C. M. Chan and William M. Pandak and Douglas M. Heuman and Z Rano Vlahcevic},
  journal={Kidney international},
  year={1993},
  volume={44 4},
  pages={789-94}
}
Hypercholesterolemia frequently accompanies the nephrotic syndrome, but the mechanism responsible for elevation of plasma cholesterol is poorly understood. Specifically, the contribution of abnormal hepatic cholesterol metabolism to elevated concentrations of serum cholesterol has never been studied in depth. The objective of the present study was to define… CONTINUE READING