Studies of HLA, fertility and mate choice in a human isolate.
@article{Ober1999StudiesOH, title={Studies of HLA, fertility and mate choice in a human isolate.}, author={Carole Ober}, journal={Human reproduction update}, year={1999}, volume={5 2}, pages={ 103-7 } }
The role of human leukocyte antigen (HLA) genes in pregnancy and in human mate choice has been investigated in the Hutterites, an inbred population of European origins. High-resolution HLA haplotypes were defined by alleles at 16 loci in >1000 Hutterites. Prospective studies of pregnancy outcome previously demonstrated increased fetal loss rates among Hutterite couples matching for HLA-B antigens (P = 0.033) or for the entire 16-locus haplotype (P = 0.002). Among living children of couples…
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