Studies of ACTH secretion control in 116 cases of Cushing's syndrome.

@article{Raux1975StudiesOA,
  title={Studies of ACTH secretion control in 116 cases of Cushing's syndrome.},
  author={M. C. Raux and Michel Binoux and Jean Pierre Luton and Micheline Gourmelen and F J Girard},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1975},
  volume={40 2},
  pages={186-97}
}
Plasma ACTH (normal value: 0.16 plus or minus mU/100 ml) was measured in 116 patients with Cushing's syndrome, using a bioassay including dynamic tests and sequential determinations. In 10 patients with adrenal tumors ACTH levels were nondetectable (ND) or low, and usually nonstimulatable. In 10 patients with ectopic ACTH secretion high levels (0.42 plus or minus 0.07 mU/100 ml) were measured. The extracts of 6 tumors yielded an ACTH-like substance. Forty-three patients with Cushing's disease… CONTINUE READING

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