Studies into the transplantation biology of ultraviolet light-induced tumors.

  title={Studies into the transplantation biology of ultraviolet light-induced tumors.},
  author={Raymond A. Daynes and C. W. Spellman and Jerold G. Woodward and Donald A. Stewart},
  volume={23 4},
The majority of skin tumors induced in mice by ultraviolet (UV) light are rejected when implanted into normal syngeneic recipients. Subcarcinogenic levels of UV light exposure render the normally resistant mice susceptible to tumor challenge. The immunoregulatory effect of UV light appears to be additive, since the growth rate of a tumor transplant is dependent upon the length of UV exposure administered prior to implantation. This suppressive influence does not appear to be directly mediated… CONTINUE READING

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