Studies in vivo and in vitro on effects of PGE2 on colonic motility in rabbits.

@article{Burakoff1992StudiesIV,
  title={Studies in vivo and in vitro on effects of PGE2 on colonic motility in rabbits.},
  author={Robert B Burakoff and William H. Percy},
  journal={The American journal of physiology},
  year={1992},
  volume={262 1 Pt 1},
  pages={
          G23-9
        }
}
  • Robert B Burakoff, William H. Percy
  • Published in
    The American journal of…
    1992
  • Biology, Medicine
  • Prostaglandins (PG) of the E series are synthesized throughout the gastrointestinal tract, and their elevated levels have been reported in many diarrheal states, including inflammatory bowel disease. It is already known that PGE2 has region-specific and muscle layer-specific effects in different areas of the intestine. The aim of this study was to evaluate possible dose-related motor effects of PGE2 on rabbit proximal and distal colon both in vivo and in vitro. We found that, in the proximal… CONTINUE READING

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