Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide.

@article{Snchez1967StudiesIP,
  title={Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide.},
  author={R. S{\'a}nchez and J. Ferris and L. Orgel},
  journal={Journal of molecular biology},
  year={1967},
  volume={30 2},
  pages={
          223-53
        }
}
  • R. Sánchez, J. Ferris, L. Orgel
  • Published 1967
  • Chemistry, Medicine
  • Journal of molecular biology
  • There is much evidence suggesting that hydrogen cyanide was important in prebiotic synthesis. Here we discuss the relevant aqueous solution chemistry, since we believe it to be pertinent to prebiotic synthesis. In mildly alkaline solutions (pH 7 to 10) two modes of destruction compete. Hydrolysis to formamide and formic acid is first-order in HCN, while polymerization involving the formation of C C bonds is quadratic in HCN. Within the pH range 8 to 9 and the temperature range 0 to 60°C, the… CONTINUE READING
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