Studies in fetal wound healing: II. A fetal environment accelerates fibroblast migration in vitro.

@article{Longaker1989StudiesIF,
  title={Studies in fetal wound healing: II. A fetal environment accelerates fibroblast migration in vitro.},
  author={Michael Thornton Longaker and Michael R. Harrison and Jacob Charles Langer and Timothy M. Crombleholme and Edward Donald Verrier and R S Spendlove and Robert Stern},
  journal={Journal of pediatric surgery},
  year={1989},
  volume={24 8},
  pages={793-7; discussion 798}
}
We have used an in vitro model of wound healing using scratches made in a confluent monolayer of fibroblasts. The effects of fetal calf and postnatal calf serum on the migration of fibroblasts were compared. Differences between fetal and calf serum-incubated fibroblasts grown on coverslips were observed within 15 minutes of exposure. Cells in fetal serum began to change both shape and orientation and to move into the trough created by the scratch. The fibroblasts incubated in fetal calf serum… CONTINUE READING

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