Studies concerning the mechanism of action of acetoacetyl succinic thiophorase by use of O18.

@article{Falcone1959StudiesCT,
  title={Studies concerning the mechanism of action of acetoacetyl succinic thiophorase by use of O18.},
  author={A. Falcone and P. Boyer},
  journal={Archives of biochemistry and biophysics},
  year={1959},
  volume={83 1},
  pages={
          337-44
        }
}
  • A. Falcone, P. Boyer
  • Published 1959
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
Abstract In the reaction of succinate-O18 with acetoacetyl coenzyme A to form succinyl coenzyme A and acetoacetate, as catalyzed by acetoacetyl succinic thiophorase, O18 from the succinate appears in the carboxyl group of acetoacetate. An enzymic mechanism considered consistent with these findings involves formation of mixed anhydrides as intermediates. 
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