Sts1 plays a key role in targeting proteasomes to the nucleus.


The evidence that nuclear proteins can be degraded by cytosolic proteasomes has received considerable experimental support. However, the presence of proteasome subunits in the nucleus also suggests that protein degradation could occur within this organelle. We determined that Sts1 can target proteasomes to the nucleus and facilitate the degradation of a… (More)
DOI: 10.1074/jbc.M110.135863


14 Figures and Tables