Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells.

Abstract

P-selectin glycoprotein ligand-1 (PSGL-1) is a disulfide-bonded homodimeric mucin-like glycoprotein on leukocytes that interacts with both P- and E-selectin. In this report we describe the structures of the Ser/Thr-linked O-glycans of PSGL-1 synthesized by HL-60 cells metabolically radiolabeled with 3H-sugar precursors. In control studies, the O-glycans on… (More)

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Cite this paper

@article{Wilkins1996StructuresOT, title={Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells.}, author={Patricia P. Wilkins and Rodger P McEver and Ron Cummings}, journal={The Journal of biological chemistry}, year={1996}, volume={271 31}, pages={18732-42} }