Structures of mollusc shell framework proteins

  title={Structures of mollusc shell framework proteins},
  author={Shu Sudo and Takahiko Fujikawa and Takeshi Nagakura and Takeshi Ohkubo and K Sakaguchi and M. Tanaka and Kunio Nakashima and T. Takahashi},
Mollusc shells consist of the nacreous mother-of-pearl layer and the prismatic layer. Both layers are microlaminate composites of CaCO3 crystals (aragonite in the nacre and calcite in the prismatic layer) and biopolymers. The main biopolymers are structural proteins, insoluble in water and methanoic acid, which determine the framework of each shell layer and bind soluble polyanionic proteins which determine the type of CaCO3 crystal that grows. Here we report the sequences and structures of the… 
Progress of Molluscan Nacre Proteins Research
Nacre composing the inner layer of mollusk shell is a typical product of biomineralization. While main components of the organics in nacre are proteins, which mediate its distinctive lamellate
Matrix Proteins in the Outer Shells of Molluscs
The matrix proteins identified to date from the shells of molluscs, their structural characteristics, and their roles in shell formation are reviewed.
Molecular approaches to understand biomineralization of shell nacreous layer.
The recent research advances on nacre biomineralization of shells from bivalves and gastropods are introduced, which mainly focus on analysis of the micro- and nano-structure and components of shell nacreous layers, and investigations of the characteristics and functions of matrix proteins from nacre.
Mollusk shell formation: a source of new concepts for understanding biomineralization processes.
The biological approach to forming crystals is proving to be most surprising. Mollusks build their shells by using a hydrophobic silk gel, very acidic aspartic acid rich proteins, and apparently also
Different secretory repertoires control the biomineralization processes of prism and nacre deposition of the pearl oyster shell
It is unambiguously demonstrate that prisms and nacre are assembled from very different protein repertoires, which suggests that these layers do not derive from each other.
Mollusk shell structures and their formation mechanism1
The structures of mollusk shells and their process of formation are summarized, together with the analysis of various organic matrices related to shell calcification, to lead to the development of new inorganic–organic hybrid materials for various applications.
The formation and mineralization of mollusk shell.
Today, the shell matrix appears as a whole system, which regulates protein-mineral, protein-protein, and epithelium-Mineral interactions, and these aspects should be taken in account for the future models of shell formation.
Acidic Shell Proteins of the Mediterranean Fan Mussel Pinna nobilis.
It is shown that extremely acidic intracrystalline proteins such as caspartin interact with calcium carbonate at different scales, from micrometric to crystal lattice levels.


Control of crystal phase switching and orientation by soluble mollusc-shell proteins
IN the initial stages of the biomineralization of abalone shells, a primer layer of oriented calcite crystals grows on a nucleating protein sheet1,2. The deposition of this primer is followed by an
Molecular recognition in biomineralization
  • S. Mann
  • Chemistry, Materials Science
  • 1988
The deposition of precise arrays of inorganic crystals in many organisms involves controlled nucleation at interfaces between the crystals and substrate macromolecules. These inorganic-organic
Present address: Research Unit, Mikimoto Pharmaceutical Co., Ise, Mie 516, Japan
  • Proc. Natl Acad. Sci. USA
  • 1996