Structures of human genes coding for cytokine LD78 and their expression.

  title={Structures of human genes coding for cytokine LD78 and their expression.},
  author={Makoto Nakao and H. Nomiyama and Koichi Shimada},
  journal={Molecular and cellular biology},
  volume={10 7},
LD78 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing, and tumorigenesis. Southern blot analysis of the EcoRI-digested human genomic DNAs, using previously isolated LD78 cDNA as a probe, showed that in each individual there are 4.2- and 4.8-kilobase-pair (kb) fragments and that some have an additional 6.5-kb fragment. The 4.2-kb fragment contained genomic DNA sequences corresponding to the LD78 cDNA and was named the… CONTINUE READING


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