Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase.

@article{ShinzawaItoh2007StructuresAP,
  title={Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase.},
  author={Kyoko Shinzawa-Itoh and Hiroshi Aoyama and Kazumasa Muramoto and Hirohito Terada and Tsuyoshi Kurauchi and Yoshiki Tadehara and Akiko Yamasaki and Takashi Sugimura and Sadamu Kurono and Kazuo Tsujimoto and Tsunehiro Mizushima and Eiki Yamashita and Tomitake Tsukihara and Shinya Yoshikawa},
  journal={The EMBO journal},
  year={2007},
  volume={26 6},
  pages={1713-25}
}
All 13 lipids, including two cardiolipins, one phosphatidylcholine, three phosphatidylethanolamines, four phosphatidylglycerols and three triglycerides, were identified in a crystalline bovine heart cytochrome c oxidase (CcO) preparation. The chain lengths and unsaturated bond positions of the fatty acid moieties determined by mass spectrometry suggest that each lipid head group identifies its specific binding site within CcOs. The X-ray structure demonstrates that the flexibility of the fatty… CONTINUE READING

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