Structures and mechanisms of vesicle coat components and multisubunit tethering complexes.

@article{Jackson2012StructuresAM,
  title={Structures and mechanisms of vesicle coat components and multisubunit tethering complexes.},
  author={Lauren P Jackson and Daniel K{\"u}mmel and Karin M Reinisch and David R. Owen},
  journal={Current opinion in cell biology},
  year={2012},
  volume={24 4},
  pages={475-83}
}
Eukaryotic cells face a logistical challenge in ensuring prompt and precise delivery of vesicular cargo to specific organelles within the cell. Coat protein complexes select cargo and initiate vesicle formation, while multisubunit tethering complexes participate in the delivery of vesicles to target membranes. Understanding these macromolecular assemblies has greatly benefited from their structural characterization. Recent structural data highlight principles in coat recruitment and uncoating… CONTINUE READING

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