Structures and cytotoxic evaluation of new and known acyclic Ene-Ynes from an American Samoa Petrosia sp. Sponge.

@article{Mejia2013StructuresAC,
  title={Structures and cytotoxic evaluation of new and known acyclic Ene-Ynes from an American Samoa Petrosia sp. Sponge.},
  author={Eric J. Mejia and Lindsay B Magranet and Nicole Joy de Voogd and Karen Tendyke and Dayong Qiu and Young Yongchun Shen and Zhongrui Zhou and Phillip Crews},
  journal={Journal of natural products},
  year={2013},
  volume={76 3},
  pages={425-32}
}
Four new compounds, (-)-petrosynoic acids A-D (1-4), and five known congeners, pellynols A (5), C (6), D (7), F (8), and I (9), were isolated from a Petrosia sp. marine sponge collected in American Samoa. Isolation work was guided by cytotoxicity against human lung cancer cells (H460). The structures of the C31-C33 polyacetylenes (1-9) were determined on the basis of 1D- and 2D-NMR analysis, mass spectrometry, and comparison of specific rotation values. Compounds 1-9 were found to be broadly… CONTINUE READING
1 Citations
2 References
Similar Papers

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-2 of 2 references

Anti-Cancer Agents Med

  • A. Siddiq, V. Dembitsky
  • Chem. 2008,
  • 2008

Bioactive Polyacetylenic Compounds from Marine Sponges

  • J. H. Jung, K. S. Im, B. H. Bae
  • Biomaterials from Aquatic and Terrestrial…

Similar Papers

Loading similar papers…