Structure prediction for CASP7 targets using extensive all‐atom refinement with Rosetta@home

@article{Das2007StructurePF,
  title={Structure prediction for CASP7 targets using extensive all‐atom refinement with Rosetta@home},
  author={Rhiju Das and Bin Qian and Srivatsan Raman and Robert M. Vernon and James M Thompson and Philip Bradley and Sagar D. Khare and Michael D. Tyka and Divya Bhat and Dylan Chivian and David E. Kim and William Sheffler and Lars Malmstr{\"o}m and Andrew M Wollacott and Chu Wang and Ingemar Andr{\'e} and David Baker},
  journal={Proteins: Structure},
  year={2007},
  volume={69}
}
We describe predictions made using the Rosetta structure prediction methodology for both template‐based modeling and free modeling categories in the Seventh Critical Assessment of Techniques for Protein Structure Prediction. For the first time, aggressive sampling and all‐atom refinement could be carried out for the majority of targets, an advance enabled by the Rosetta@home distributed computing network. Template‐based modeling predictions using an iterative refinement algorithm improved over… Expand
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