Structure of the hexapeptide xenobiotic acetyltransferase from Pseudomonas aeruginosa.

@article{Beaman1998StructureOT,
  title={Structure of the hexapeptide xenobiotic acetyltransferase from Pseudomonas aeruginosa.},
  author={Todd W Beaman and Michele Sugantino and Steven L. Roderick},
  journal={Biochemistry},
  year={1998},
  volume={37 19},
  pages={6689-96}
}
The crystal structure of the xenobiotic acetyltransferase from Pseudomonas aeruginosa PA103 (PaXAT) has been determined, as well as that of its complex with the substrate chloramphenicol and the cofactor analogue desulfo-coenzyme A. PaXAT is a member of the large hexapeptide acyltransferase family of enzymes that display tandem repeated copies of a six-residue hexapeptide repeat sequence motif encoding a left-handed parallel beta helix (L betaH) structural domain. The xenobiotic… CONTINUE READING

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