Structure of the gene encoding the mouse 47-kDa heat-shock protein (HSP47).

@article{Hosokawa1993StructureOT,
  title={Structure of the gene encoding the mouse 47-kDa heat-shock protein (HSP47).},
  author={Nobuko Hosokawa and Hajime Takechi and Sadaki Yokota and Kazunori Hirayoshi and Kazuhiro Nagata},
  journal={Gene},
  year={1993},
  volume={126 2},
  pages={187-93}
}
HSP47, a 47-kDa heat-shock protein (HSP), is a member of a group of HSPs with the unique characteristics of collagen binding as well as transformation sensitivity. The protein belongs to the serpin (serine protease inhibitor) superfamily as determined from its amino acid sequence homology. We have isolated and characterized the mouse HSP47 including about 1 kb of the 5'-flanking region. This gene spans about 7.8 kb, consisting of six exons separated by five introns. This exon-intron structure… CONTINUE READING