Structure of the gene coding for the human early lymphocyte activation antigen CD69: a C-type lectin receptor evolutionarily related with the gene families of natural killer cell-specific receptors.

@article{Santis1994StructureOT,
  title={Structure of the gene coding for the human early lymphocyte activation antigen CD69: a C-type lectin receptor evolutionarily related with the gene families of natural killer cell-specific receptors.},
  author={Ana G. Santis and Manuel L{\'o}pez-Cabrera and Joerg Hamann and Michael Strauss and Francisco S{\'a}nchez-Madrid},
  journal={European journal of immunology},
  year={1994},
  volume={24 7},
  pages={1692-7}
}
CD69 is the earliest inducible cell surface glycoprotein acquired during lymphoid activation. CD69 functions as a signal transmitting receptor involved in cellular activation events including proliferation and the induction of specific genes. This molecule is a member of a supergene family of type-II integral membrane proteins with C-type lectin domains. We have herein studied the genomic structure of the human gene encoding CD69. The coding sequence is divided into five exons separated by four… CONTINUE READING

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