Structure of the full-length yeast Arp7-Arp9 heterodimer.

  title={Structure of the full-length yeast Arp7-Arp9 heterodimer.},
  author={Joel Lobsiger and Yvonne Hunziker and Timothy J. Richmond},
  journal={Acta crystallographica. Section D, Biological crystallography},
  volume={70 Pt 2},
The nuclear actin-related proteins Arp7 and Arp9 are components of the yeast SWI/SNF and RSC chromatin-remodelling complexes. The 3.1 Å resolution crystal structure reported here shows that the full-length Arp7 and Arp9 proteins exist as a dimer without a requirement for additional polypeptides. Of the 11 actin-related proteins, Arp7 and Arp9 are the only two directly demonstrated to form a dimer within this family. The Arp7-Arp9 heterodimer is unlikely to form an actin-like filament based on… CONTINUE READING