Structure of the dodecahedral penton particle from human adenovirus type 3.

@article{Fuschiotti2006StructureOT,
  title={Structure of the dodecahedral penton particle from human adenovirus type 3.},
  author={Patrizia Fuschiotti and Guy Schoehn and Pascal Fender and C{\'e}line M S Fabry and Elizabeth A. Hewat and Jadwiga Chroboczek and Rob W H Ruigrok and James F Conway},
  journal={Journal of molecular biology},
  year={2006},
  volume={356 2},
  pages={510-20}
}
The sub-viral dodecahedral particle of human adenovirus type 3, composed of the viral penton base and fiber proteins, shares an important characteristic of the entire virus: it can attach to cells and penetrate them. Structure determination of the fiberless dodecahedron by cryo-electron microscopy to 9 Angstroms resolution reveals tightly bound pentamer subunits, with only minimal interfaces between penton bases stabilizing the fragile dodecahedron. The internal cavity of the dodecahedron is… CONTINUE READING
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