Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.

@article{Gulbis2000StructureOT,
  title={Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.},
  author={Jacqueline M. Gulbis and Mingkang Zhou and Sabine Mann and Roderick MacKinnon},
  journal={Science},
  year={2000},
  volume={289 5476},
  pages={123-7}
}
The structure of the cytoplasmic assembly of voltage-dependent K+ channels was solved by x-ray crystallography at 2.1 angstrom resolution. The assembly includes the cytoplasmic (T1) domain of the integral membrane alpha subunit together with the oxidoreductase beta subunit in a fourfold symmetric T1(4)beta4 complex. An electrophysiological assay showed that… CONTINUE READING