Structure of the chicken gene for SNAP-25 reveals duplicated exon encoding distinct isoforms of the protein.

@article{Bark1993StructureOT,
  title={Structure of the chicken gene for SNAP-25 reveals duplicated exon encoding distinct isoforms of the protein.},
  author={I C Bark},
  journal={Journal of molecular biology},
  year={1993},
  volume={233 1},
  pages={67-76}
}
  • I C Bark
  • Published 1993 in Journal of molecular biology
SNAP-25 (synaptosomal associated protein of 25 kDa) is a neuronal-specific but non-uniformly expressed protein. Expression is correlated to the time of synaptogenesis and SNAP-25 protein is found predominantly in presynaptic fields. Here we report the cloning and characterization of the SNAP-25 chicken gene. The gene spans more than 65 kb of genomic DNA and is interrupted into nine different exons. Identification of the 5'-end of the mRNA showed that transcriptional initiation is heterogeneous… CONTINUE READING
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