Structure of the alpha-form of poly[d(A)].poly[d(T)] and related polynucleotide duplexes.

@article{Park1987StructureOT,
  title={Structure of the alpha-form of poly[d(A)].poly[d(T)] and related polynucleotide duplexes.},
  author={Hee Sung Park and S. Arnott and Rengaswami Chandrasekaran and R P Millane and F. Campagnari},
  journal={Journal of molecular biology},
  year={1987},
  volume={197 3},
  pages={513-23}
}
The alpha-form of poly[d(A)].poly[d(T)], observed in fibers at high (greater than 80%) relative humidity, is a 10-fold double-helical structure of pitch 3.2 nm. This new X-ray analysis shows that the two strands of the double helix are of the same kind conformationally and both B-like in containing C-2'-endo-puckered deoxyribose rings. Nevertheless, the two strands are different enough for the overall morphology of the duplex to resemble that of the heteromerous model for the drier (beta) form… CONTINUE READING