Structure of the SSB-DNA polymerase III interface and its role in DNA replication.

Abstract

Interactions between single-stranded DNA-binding proteins (SSBs) and the DNA replication machinery are found in all organisms, but the roles of these contacts remain poorly defined. In Escherichia coli, SSB's association with the χ subunit of the DNA polymerase III holoenzyme has been proposed to confer stability to the replisome and to aid delivery of… (More)
DOI: 10.1038/emboj.2011.305

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