Structure of the SHV-1 beta-lactamase.

  title={Structure of the SHV-1 beta-lactamase.},
  author={Alexandre P. Kuzin and Michiyoshi Nukaga and Yuri Nukaga and Andrea M. Hujer and Robert A. Bonomo and James R. Knox},
  volume={38 18},
The X-ray crystallographic structure of the SHV-1 beta-lactamase has been established. The enzyme crystallizes from poly(ethylene glycol) at pH 7 in space group P212121 with cell dimensions a = 49.6 A, b = 55.6 A, and c = 87.0 A. The structure was solved by the molecular replacement method, and the model has been refined to an R-factor of 0.18 for all data in the range 8.0-1.98 A resolution. Deviations of model bonds and angles from ideal values are 0.018 A and 1.8 degrees, respectively… CONTINUE READING

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