Structure of the N-terminal domain of the effector protein LegC3 from Legionella pneumophila.

Abstract

Legionella pneumophila secretes over 300 effectors during the invasion of human cells. The functions of only a small number of them have been identified. LegC3 is one of the identified effectors, which is believed to act by inhibiting vacuolar fusion. It contains two predicted transmembrane helices that divide the protein into a larger N-terminal domain and… (More)
DOI: 10.1107/S139900471302991X

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