Structure of the Integrin αIIb Transmembrane Segment


Integrin cell-adhesion receptors transduce signals bidirectionally across the plasma membrane via the single-pass transmembrane segments of each and subunit. While the 3 transmembrane segment consists of a linear 29-residue -helix, the structure of the IIb transmembrane segment reveals a linear 24-residue -helix (Ile-966–Lys-989) followed by a backbone… (More)


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@inproceedings{Lau2008StructureOT, title={Structure of the Integrin αIIb Transmembrane Segment}, author={Tong-Lay Lau and Varun Dua and Tobias S Ulmer and Malcolm W Macarthur and David S. Moss}, year={2008} }